Lebrun Labs
At Lebrun Labs LLC our expertise centers on nonanimal toxicology test method development and application. This includes the OptiSafe (OS) chemical based test for identifying and classifying eye irritants and the In Vitro Depth of Injury Eye Irritation Test (IVD EIT) for classification of reversible eye irritants. In addition, the state-of-the art laboratory provides additional nonanimal toxicology testing and research services consistent with our expertise.
Toxicology Products
OptiSafe
The OptiSafe test is a novel, shelf-stable, test tube-based test that can be used to discriminate ocular irritants/corrosives from nonirritants and does not use animal tissues or cells. The test method determines if an unknown substance is an ocular nonirritant by measuring and comparing chemical models for three variables: 1) damage to the corneal stroma (water-soluble molecules), 2) damage to phospholipid bilayers (water-insoluble molecules), and 3) the potential to induce pH extremes in a system (pH buffering system of the eye).
Read More
Depth of Injury
Lebrun Labs LLC has been developing and improving the in vitro depth of injury (IVD) ocular irritation test method to serve as an accurate, reliable way to test consumer products and chemicals for their irritancy potential. The purpose of this test method is to detect the full range of ocular irritants; including reversible damage. Although this test method is still in development, we welcome collaborations with interested parties. In addition, we provide customized “research-level” DoI testing services.
Read More
Contract Research
Lebrun Labs LLC provides support to the pharmaceutical, biotechnology, medical device, and other biomedical industries by providing research services on a contract basis.Cancer Research
Lebrun Labs LLC can perform a wide range of cell-based efficacy and toxicity studies on your candidate compound or mixture.
Read More
Developmental Biology Research
Lebrun Labs can perform cell- and tissue-based studies to evaluate compounds and mixtures that interact with specific developmental and related processes as well as set up test systems that require cell and tissue differentiation and analysis.
Read More
Toxicology Research
Lebrun Labs provides customized toxicity solutions, including mixture toxicity evaluation and characterization.
Read More