Depth of Injury Eye Irritation Test

The Depth of Injury (DoI) Eye Irritation Test is now available as a “research level” service.

Although this test method is still in development, we welcome collaborations with interested parties. We can provide customized “research-level” DoI testing services. Contact us for more information. 

This work has been recently published in Toxicology In Vitro: 

An in vitro depth of injury prediction model for a histopathologic classification of EPA and GHS eye irritants
Stewart Lebrun, Yilu Xie , Sara Chavez , Roxanne Chan , James V Jester
2019 Dec;61:104628.  doi: 10.1016/j.tiv.2019.104628.  Epub 2019 Aug 13.

In vitro DoI is being developed with funding from an NIEHS Small Business Innovative Research Grant: “A Nonanimal Kit and Service for the Detection of Reversible Ocular Irritants.” Research was supported by the NIEHS of the National Institutes of Health under Award Number R43ES031881. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

For additional information contact: